I-acetylene ikhiqizwa ngokwentengiso ngokusabela phakathi kwe-calcium carbide namanzi, futhi iwumkhiqizo wokukhiqizwa kwe-ethylene.
I-acetylene iyigesi ebalulekile yokusebenza kwensimbi, ingasabela nge-oxygen ukuze ikhiqize ilangabi lokushisa eliphezulu, elisetshenziselwa imishini, i-fitters, i-welding kanye nokusika. I-acetylene welding iyindlela evamile yokucubungula enganamathisela izingxenye ezimbili noma ngaphezulu zensimbi ndawonye ukuze kuzuzwe inhloso yokuxhumana okuqinile. Ngaphezu kwalokho, i-acetylene ingasetshenziswa futhi ukusika izinsimbi ezihlukahlukene, kuhlanganise nensimbi engagqwali, insimbi ne-aluminium. I-acetylene ingasetshenziselwa ukukhiqiza amakhemikhali afana ne-acetylol alcohols, i-styrene, i-esters ne-propylene. Phakathi kwazo, i-acetynol iyinhlangano evame ukusetshenziswa kakhulu ye-organic synthesis intermediate, engasetshenziswa ukwenza amakhemikhali afana ne-acetynoic acid ne-alcohol ester. I-styrene iyinhlanganisela ye-organic esetshenziswa kakhulu kumapulasitiki, irabha, odayi nama-synthetic resins. I-acetylene ingasetshenziswa emkhakheni wezokwelapha ekwelapheni okufana ne-anesthesia kanye ne-oxygen therapy. I-Oxyacetylene welding, esetshenziswa ekuhlinzeni, iyindlela ethuthukisiwe yokusika izicubu ezithambile nokususwa kwesitho. Ngaphezu kwalokho, i-acetylene isetshenziselwa ukwakhiwa kwemishini yezokwelapha njengama-scalpels, izibani ezihlukahlukene zezokwelapha kanye nama-dilators. Ngaphezu kwezinkambu ezishiwo ngenhla, i-acetylene ingasetshenziswa futhi ukwenza izinto ezihlukahlukene ezifana nerabha, amakhadibhodi kanye nephepha. Ngaphezu kwalokho, i-acetylene ingasetshenziswa futhi njenge-feedstock yokukhiqiza i-olefin kanye nezinto ezikhethekile zekhabhoni, kanye negesi esetshenziselwa izinqubo zokukhiqiza ezifana nokukhanyisa, ukwelashwa kokushisa nokuhlanza.