Sulfur hexafluoride is produced by the direct fluorination of pure (elemental) sulfur, usually by companies that produce fluorine for other purposes, such as the production of fluorocarbons.

Sulfur hexafluoride is one of the important raw materials for metal smelting. It has good insulation performance and arc elimination performance, and is widely used in the power industry, such as circuit breakers, high-voltage switches, high-voltage transformers. Sulfur hexafluoride is used as an anesthetic in situations that require general anesthesia, such as surgery. It has a higher anesthetic effect than nitric oxide and can achieve better analgesic effect. Sulfur hexafluoride is mainly used for clinical diagnosis, and can be used for ultrasonic cardiography, large blood vessel Doppler, small blood vessel Doppler and other examinations. Sulfur hexafluoride can be used for gas protection to prevent oxygen, water and other impurities from entering certain equipment or pipes. Sulfur hexafluoride is used to treat focal liver lesions, which can be diagnosed and treated more accurately by ultrasound. Sulfur hexafluoride is widely used in the metal smelting industry because of its ability to leave traces of sulfur in the atmosphere, which can be used to detect and trace pollutants.

Sulfur hexafluoride has important uses in electronics manufacturing, where it can be combined with fluorine atoms to form high-speed electric currents, enabling precise measurement and control in electronic devices. Sulfur hexafluoride can be used as a fungicide, which has a strong killing effect on microorganisms such as bacteria, fungi and viruses. Sulfur hexafluoride is one of the refrigerants commonly used in refrigerators and air conditioning systems to absorb heat and lower temperatures.