The main source of helium is natural gas wells. It is obtained through liquefaction and stripping operations.Due to the shortage of helium in the world, many applications have recovery systems to recover helium.
Helium has important applications in the aerospace sector, such as as a delivery and pressurization gas for rocket and spacecraft propellants, and as a pressurization agent for ground and flight fluid systems. Because of its small density and stable nature, helium is often used to fill weather observation balloons and entertainment balloons to provide lift. Helium is safer than flammable hydrogen because it does not burn or cause an explosion. Liquid helium can provide an extremely low temperature environment for use in superconducting technology and magnetic resonance imaging (MRI), maintaining the extremely low temperature conditions required for superconducting magnets.

In the medical field, helium is used to maintain a cryogenic environment for superconductors in magnetic resonance imaging devices and for complementary treatments such as respiratory support. Helium acts as an inert protective gas to prevent oxidation reactions during welding and is also used in gas detection and leak detection technology to ensure the tightness of equipment and systems. In scientific research and laboratories, helium is often used as a carrier gas for gas chromatography, providing a stable experimental environment. In the semiconductor manufacturing process, helium is used for cooling and to create a clean environment, ensuring the stability of the production process and product quality.